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You may have heard that CBD oils can be effective supplements to assist in weight loss. Let’s take a look at the best CBD oils for weight loss, their safety, and the evidence behind them.
Best CBD Oil for Weight Loss
With hundreds of CBD oil brands on the US market today, it can be daunting to find the right one to fit your needs on your own. That’s why we have researched the best CBD products for weight loss, who they’re best suited to, and who should avoid them.
1. Cornbread Hemp – Best CBD Oil for Weight Loss
Only hemp flowers are used to maximize cannabinoid content.
USDA Certified Organic hemp, carried in organic medium-chain triglyceride (MCT) oil.
Full-spectrum hemp extract to support the entourage effect.
Board-certified oncology pharmacist on Board of Advisors as resident medical expert.
Who Is Cornbread Hemp Best For?
Cornbread Hemp suits those who need optimum endocannabinoid system support, to better lose weight by converting white fat to brown fat. As brown fat tissue burns energy, you can more easily maintain a lower body weight in your healthy range .
The CBD oil is also versatile. If you have trouble sleeping at night, the Whole Flower oil is here to help with its higher THC concentration. On the other hand, the Distilled Oil is a “pure and smooth” formulation with a lower level of other cannabinoids, including less THC.
Who Should Avoid Cornbread Hemp?
The Whole Flower CBD oil contains the maximum legal concentration of THC, at 0.3%. If you are particularly sensitive or take higher doses, you may be at a greater risk of issues with safety and side effects such as dizziness and tiredness.
Potential Side Effects
Cornbread Hemp is an outstanding brand for quality, deriving its full-spectrum CBD oil from only hemp flowers.
2. Spruce – Best CBD Oil for Weight Loss and Anxiety
750mg of CBD, or 25mg per 1ml dose (standard), 80mg of CBD per dose in the Lab-Grade formulation.
High-potency ethanol extraction using moonshine.
Spruce Rest available, with a higher cannabinol content.
With 0.3% THC, there is a risk that you could test positive for cannabis.
Can have a more bitter taste.
Who Is Spruce Best For?
Those who struggle to reach a healthy weight as a result of overeating in response to anxiety could benefit most from Spruce. Additionally, customers looking for a high potency to maximize endocannabinoid system support may find better results.
Spruce is implied to be high in pinene, a terpene with potential anti-anxiety benefits. Pinene does not act on the cannabinoid receptors. Instead, it increases the response to the calming neurotransmitter, GABA, more than supplementing with GABA itself .
Who Should Avoid Spruce?
Like Cornbread Hemp, taking Spruce CBD oil may be unsafe if you must undergo regular drug testing. The calming effects of Spruce’s terpene profile can increase the potentially sedative effects of CBD too. If you are already taking supplements or medications that may cause drowsiness, Spruce may not be for you.
Potential Side Effects
Spruce is a wonderfully calming blend for those with anxiety, and may relieve stress-eating as a result.
3. Absolute Nature – Best for Pain Management and Weight Loss
1:1 CBD:CBG formulations available.
Comprehensive payment assistance service.
Commitment to sustainable practices.
Who Is Absolute Nature Best For?
Absolute Nature is best for those struggling with unwanted body weight because pain and inflammation interfere with exercise. CBG is shown to have a stronger anti-inflammatory effect than THC, which can relieve pain and protect tissues from everyday damage. It may also be a muscle relaxant, as it can increase GABA more than THC or CBD .
Who Should Avoid Absolute Nature?
You may need to use caution if you take other muscle-relaxant or GABA-increasing medication with this blend.
Potential Side Effects
Absolute Nature’s CBD:CBG oil may pack extra anti-inflammatory power to soothe sore muscles after a workout.
4. NuLeaf Naturals – Best for Value for Money
Multi-cannabinoid option to bring you a balanced profile of CBD, CBG, CBC, and CBN.
Significant quantities of CBG, CBN, and other cannabinoids for the entourage effect.
CBC, CBG, and CBN-dominant full-spectrum extracts to maximize the benefits for inflammation and sleep .
Assistance program to make products more affordable for not only veterans and low-income customers, but also active duty personnel and first responders (e.g. nurses and police officers).
Who Is NuLeaf Naturals Best For?
Achieving and keeping a healthy body weight doesn’t happen overnight, so NuLeaf Naturals is best for those on a budget as it makes long-term supplementation more affordable.
For example, one 900mg bottle of CBD oil costs $79.00, but a pack of six is only $394.00, a saving of $86.00. Additionally, the CBC, CBG, and CBN-dominant options give you the ability to discover and choose which type is best for you.
Who Should Avoid NuLeaf Naturals?
NuLeaf Naturals’ CBN-dominant oils may be too sedative, so avoid these if you take other sleep aids or calming medications or supplements.
Potential Side Effects
NuLeaf Naturals gives you the option to choose larger packs with more value for money, as well as oils with different dominant cannabinoids.
5. Vital Plan – Best Full Spectrum Oil for Weight Loss
Six times more terpenes than similar CBD products.
Biodynamic cultivation, a step beyond organic agriculture.
Free joint and muscle rub.
Who Is Vital Plan Best For?
Vital Plan may be best for you if you want an emphasis on full-spectrum CBD to not only turn white fat cells into energy-consuming brown fat, but also calm issues such as inflammation and anxiety (which have their own effects on body weight).
Full-spectrum CBD uses the entourage effect, a phenomenon where the terpenes and cannabinoids in hemp have more benefits together than alone .
Who Should Avoid Vital Plan?
People who need regular drug tests for work should avoid Vital Plan, like other brands containing some THC.
Potential Side Effects
Vital Plan contains a higher level of terpenes, which act on the endocannabinoid system in different ways, or have complementary effects. However, the exact terpenes are not disclosed.
6. Medterra CBD Oil – Best CBD Isolate
Offers CBD isolates, delivering maximum potency.
The isolate does not contain the whole hemp or cannabis plant, so you can avoid the sedative effects of CBN and THC.
Ultra Broad Spectrum blend delivers CBD, CBC, CBG, CBN, CBDV, and natural terpenes.
Who Is Medterra CBD Oil Best For?
Medterra pure CBD oil suits those who want the benefits of CBD, such as potentially reducing white fat cells and controlling appetite, but without the sedative effects of CBN or THC. If you need to undergo regular drug tests, you’re also safe.
Who Should Avoid Medterra CBD Oil?
The appetite-suppressant effects of CBD are unopposed with isolates, so if it’s only metabolic factors that caused your weight gain (instead of eating too much), Medterra’s isolates may not suit you.
Potential Side Effects
Medterra offers high-quality CBD isolates that avoid the risk of a positive drug test, or the extra sedative properties of other cannabinoids.
7. Lazarus Naturals – Best to Improve Sleep
Includes sleep tincture containing cannabigerol (CBG) and CBN, both standardized to 10mg per dose, in organic MCT oil.
Value for money at $24 for one 15ml bottle, an average of 3 cents per mg of CBD.
Assistance program for veterans, low-income customers, and those with a long-term disability. This can give you a discount of 60%.
Who Is Lazarus Naturals Best For?
Lazarus Naturals is best for those who struggle with weight gain from stress and eating too many snacks at night. Its sleep CBD oil is formulated to contain a high dose of the sedative CBN, at 10mg per serving.
Who Should Avoid Lazarus Naturals?
As stated on the label, you may have to skip Lazarus Naturals if you have been advised to avoid grapefruit or have a tree nut allergy.
Potential Side Effects
Lazarus Naturals includes tinctures specifically formulated to improve sleep and stress, preventing the need for stress-eating or midnight snacks.
8. Charlotte’s Web – Best CBD Oil for Beginners
Dosage options ranging from 7mg to 60mg of CBD per ml.
Muscle relaxant terpene profile.
Certified Organic and US Hemp Authority Certified, guaranteeing some of the highest standards of quality and transparency.
Who Is Charlotte’s Web Best For?
If you want the fat-burning benefits of hemp, but are concerned about how CBD affects you (perhaps your first dose left you feeling too sleepy), the famous Charlotte’s Web comes in lower potencies for beginners and sensitive customers.
There is a THC-free option, as well as dosage options beginning from just 7mg per serving, with the highest being 60mg of CBD per dose.
The anti-inflammatory, muscle relaxant effects of myrcene also make it suitable for post-workout recovery .
Who Should Avoid Charlotte’s Web?
Charlotte’s Web is particularly high in myrcene, a sedative and muscle relaxant terpene. Caution is advised if you take other sedative or relaxant medications or supplements.
Potential Side Effects
Charlotte’s Web includes options for the most inexperienced when it comes to CBD use, and provides a nice muscle relaxant effect.
9. Fab CBD – Best for THC:CBD Ratio
Minuscule amount of THC, well below the 0.3% limit.
Freshly made, with a 12-month shelf life.
Who Is Fab CBD Best For?
Fab CBD is ideal if you want an emphasis on increasing the proportion of brown fat cells. Besides CBD, it is high in beta-caryophyllene, which acts on the CB2 receptors. This is the mechanism that CBD works through to promote fat browning  .
Who Should Avoid Fab CBD?
You may still need to avoid Fab CBD if you are required to take drug tests.
Potential Side Effects
Fab CBD is a full-spectrum extract that only contains a slight dose of THC, but a higher amount of beta-caryophyllene.
CBD Weight Loss: Fact or Fad?
Currently, there are no FDA-approved CBD products to assist in weight management, despite their popularity in the health and wellness industry. However, some CBD oils may be effective weight loss supplements thanks to several key characteristics.
Stimulation of the Endocannabinoid System
The health benefits of CBD come from its ability to stimulate our endocannabinoid receptors, produced because the human body generates its own cannabinoids. While CB1 receptors are mostly concentrated in the nervous system, CB2 receptors are found in a number of other tissues.
Research suggests that stimulating the CB2 receptors can reduce body fat accumulation and inhibit inflammation triggered by body fat. Cannabidiol promotes “browning” of fat too. Brown fat helps to prevent obesity, as it consumes energy, unlike the inactive “white” fat. More brown fat means you will be burning calories at a higher rate .
Not all cannabinoids bring on the infamous “munchies,” a common side effect of marijuana that turns many people struggling with weight away from hemp oil. In fact, CBD may reduce appetite.
Relevant animal studies on several cannabinoids demonstrated that CBD could reduce food intake in rats, something that could translate to humans. While it didn’t delay the rat feeding patterns, CBD decreased their total food intake. You may therefore find yourself eating smaller, but not fewer, meals .
Another way CBD could aid weight loss is by helping to boost metabolism. Almost all of your body’s energy is generated in the mitochondria, “the powerhouse of the cell.” Unfortunately, they are particularly vulnerable to oxidative stress and decline in numbers with age. This may be one reason why losing weight gets harder as we age.
Laboratory research shows that CBD could protect your mitochondria, allowing them to continue burning energy. When brain cells—the most energy-demanding cell type in the body—were exposed to mitochondrial toxins, CBD was able to help them weather the storm. Higher doses were more effective, as was exposure over longer periods .
Better Exercise Performance
Another common roadblock that can thwart our need to burn calories more than we consume them is poor exercise performance, including slow recovery after a workout.
Heavy exercise leads to microscopic tissue damage in the muscles, but under healthy circumstances, our bodies are easily able to repair this and come back stronger than before. However, with age and other inflammatory conditions, this ability is impaired. Recovery slows, and we don’t benefit as much from exercise.
Fortunately, research suggests that CBD could help improve our capacity to recover from exercise, leading to better performance in the long term. By reducing cortisol and inflammation, CBD may prevent excessive damage to the muscle tissue and allow it to recover faster.
Its pain-relieving properties could help us to go further during workouts too . However, it’s important to remember this may mask injuries, so don’t use CBD to overdo exercise.
Type II diabetes is not only a consequence of diabetes, but also makes it more difficult to lose weight. Thankfully, CBD and other cannabinoids have favorable metabolic modulation properties that may even reduce your risk of developing the disease.
Research involving cannabis smokers suggests that even marijuana strains can help with weight loss, even though they often increase appetite. Cannabis smokers had lower levels of insulin resistance, more “good” cholesterol, and a lower average waist circumference. Additionally, the large NHANES population study found a reduced risk of diabetes .
Improved Sleep Helps Weight Loss
Poor sleep not only leaves us feeling foggy and tired, but can also lead to negative metabolic health effects even when we’re trying to lose weight with diet and exercise.
In a clinical study of 10 overweight adults on a moderately restrictive diet, the participants either slept for 5.5 or 8.5 hours per night. Those only sleeping 5.5 hours lost 0.6 kilograms of body fat and 2.4 kilograms of fat-free mass. Participants sleeping for 8.5 hours each night lost 1.4 kilograms of fat and 1.5 kilograms of fat-free weight.
Despite all volunteers losing weight, the efforts of the sleep-deprived group may backfire in the long term. Fat-free mass typically includes muscle, and losing muscle instead of fat can impair your exercise performance, reduce your ability to continue losing body fat, and raise your risk of poor fitness and frailty later on .
CBD may help you achieve both a healthy weight and body composition by improving sleep. Just 25mg of CBD was successful in improving sleep among two-thirds of the patients in one study, partly through its ability to reduce anxiety. However, the improvement in sleep fluctuated over time.
As the improvements in anxiety were much stronger, CBD could be right for you if you’re kept awake at night from stress and anxiety .
Choosing the Best CBD for Weight Loss
The best CBD oil depends on your individual needs. They may include whether chronic pain is keeping you from regular exercise, you are eating too much, or you are not burning calories enough because of a slow metabolism. However, there are several common factors that affect the quality and potential efficacy of CBD oils for everyone.
Nonprescription CBD products aren’t approved by the government, so we must seek quality validation through other means. Search for whether or not the product has a COA from a third-party testing lab, including the exact quantities of CBD and THC. You can also look for other cannabinoids and terpenes found in hemp, as well as contaminants.
Your chosen brand of CBD oil should disclose where their hemp is grown and how they produce their products. This reveals ethical practices in farming, alongside a general overview of the soil nutrient content and level of pollution.
Low THC Content
Hemp-derived CBD products are permitted to contain up to 0.3% THC, as it is near impossible to completely breed out the gene. Any THC content higher than this re-classifies the strain as cannabis, and puts you at a higher risk for unwanted side effects such as increased appetite.
Low (Or No) Contaminants
The soil your CBD oil was cultivated in may contain contaminants such as pesticides and heavy metals, or the raw materials could have grown mold during storage. Comprehensive third-party testing reveals the levels of each contaminant. If you cannot find a product with zero contaminants, aim for levels below the safe thresholds and below industry average.
Consumer Trust and Reputation
It’s also essential to gauge the general level of customer trust in each CBD brand you consider. Online reviews and whether the brand is independent must be considered, along with whether someone you know personally (and isn’t being paid to promote the product) has tried it.
Any FDA warning letters that have been issued are another key consideration. These can be issued for reasons including adulteration with unsafe or unapproved products, unapproved therapeutic claims, or problems with the ingredient supply chains that may affect safety or efficacy. Avoid products with warning letters for unsafe or undisclosed ingredients.
Is CBD Oil for Weight Loss Legal?
CBD oil containing less than 0.3% THC is now legal on the federal level, thanks to the 2018 Farm Bill that removed industrial hemp from the definition of “marijuana.” As the “marijuana” strains, which do contain over 0.3% THC, are still covered by the Controlled Substances Act, they are illegal on the federal level.
However, state laws vary, so if you take full-spectrum CBD oil with a higher THC content, caution is advised when traveling interstate. It is also important to remember that not all non-prescription CBD products are accurately labeled, as none are FDA-approved.
CBD for Weight Loss: The Limitations
CBD oil, like other weight management supplements, should not be relied on as the only solution to your weight issues. It acts as an aid, to help you lose weight by reducing food intake and improving physical fitness. CBD is not a substitute for a healthy diet and regular physical activity.
THC Is Linked to Increased Appetite
Besides the patchwork of legality, it’s important to avoid high concentrations of THC because it can increase food cravings. As a result, you may gain weight instead of losing it.
Studies show that THC boosts appetite through its effect on the CB1 receptors. Stimulating CB1 receptors makes food appear more desirable, leading to increased food intake and a shorter length of time between meals. This is more likely to affect your desire for junk foods, which provide little more than pleasure and calories .
Many hemp-derived CBD products have inaccurate labeling, which can mean your oil is less effective than you think, or carry a higher risk of side effects. In a study of 84 commercial CBD products, only 45% of the oils had accurate measurements of CBD. This was higher than tinctures and vaping liquid, which had accuracy rates of 25% and 12.5% respectively.
Many CBD oils had higher than advertised levels of THC too. Not only did 21% have measurable quantities of THC, but these were often high enough to make children intoxicated . If you are taking higher doses of THC, this can override the appetite-suppressant effects of CBD and lead to food cravings.
Side Effects of CBD
It is a common misconception that CBD oil has no side effects. However, CBD and other natural supplements can interact with prescription drugs or have negative effects of their own.
CBD may increase the effects of sedative medications and supplements, and may affect how well a number of prescription medications are cleared from the body. These include the antiseizure medication Tegretol, the immune-suppressing Sirolimus, and Tamoxifen.
Particular caution must be given to the risk of CBD use adding to the effect of sedatives. Some, such as opioids, slow breathing, but both these and CBD are used to reduce chronic pain. Speak to your doctor if you are currently taking opioids. Other side effects may include anemia, impaired kidney function, and allergic reactions.
CBD Not Good for Glaucoma
Glaucoma is a common indication for medical marijuana. THC can reduce the raised intraocular (inside the eye) pressure that characterizes the disease, but CBD has the opposite effect. A study on rats found that, while THC relieved pressure inside the eye by 30%, CBD increased it by 18% for more than four hours afterward .
If you are at a high risk of developing glaucoma or have the illness already, CBD may not be right for you. Unfortunately, obesity increases the average pressure inside the eye, which may put you at a greater risk of glaucoma.
One mechanism behind this may be increased oxidative stress, leading to an impaired ability to regulate pressure. The antioxidant benefits of CBD may be protective, but it is likely better to avoid CBD oil if you have glaucoma .
CBD May Increase Appetite in Some People
Everyone is different, so some supplements may have the opposite intended effect. CBD oil is no different, as studies show that it can suppress appetite in some people while increasing it in others.
Clinical studies on CBD treatment reveal increased appetite as a potential side effect for some people. For example, a survey on the experiences of families giving CBD oils to epileptic children found that 30% had a larger appetite. These findings may be relevant to customers looking for a way to burn fat faster, or may only be seen in very sick children .
However, some research shows that CBD is more likely to reduce appetite. Others still have found mixed effects of CBD oils on the desire to eat, with another study on epilepsy finding that 12 patients gained weight and 10 lost weight . You may need to try CBD products out to determine whether or not it acts as an appetite suppressant for you.
Best CBD Gummies for Weight Loss
When choosing a CBD gummy, you want that therapeutic dose of CBD and that feel-good kick of childhood candy, but without artificial ingredients. As a result, we have chosen Spruce as the best CBD gummy for weight loss. It is made of organic ingredients, and contains both 25mg of CBD and a high level of the relaxing pinene.
The Best CBD Strain for Weight Loss
CBD products are divided into full-spectrum CBD, CBD isolates, and broad-spectrum CBD. Which is best for weight loss, and what brands are our favorites?
Full Spectrum CBD for Weight Loss
Full-spectrum CBD oil contains all of the cannabinoids, terpenes, and other phytochemicals, including THC up to the legal limit. While this makes the most out of the entourage effect, maximizing anti-inflammatory and brown fat-stimulating power, THC may increase appetite.
Containing only the extract of hemp flowers, we rate Cornbread Hemp as our top full-spectrum oil.
CBD Isolate for Weight Loss
CBD isolates offer unopposed appetite-suppressing, metabolism-boosting benefits. As THC and cannabidiol exert opposing effects when it comes to appetite, and sometimes energy, you may benefit most from isolates. You also do not have to worry about failing a drug test.
Our top CBD Isolate is Spruce, with 99.6% pure CBD.
Broad Spectrum CBD for Weight Loss
A broad-spectrum CBD oil is packed with several, most, or all phytochemicals in hemp, except for THC. Some selections of phytochemicals can optimize anti-inflammatory effects, but this may leave out others with more effect on sleep or conversion of white fat cells to brown fat.
Once again, NuLeaf takes the top place, as its broad-spectrum option contains everything but THC.
How To Use CBD for Weight Loss
It’s best to take CBD oil every day if your goal is to lose weight. As its benefits in reducing inflammation, protecting the mitochondria, and suppressing excess appetite are most useful during the day, we recommend taking your first dose of CBD oil in the morning if you are (or want to be) physically active, and overeat in the daytime.
CBD is also more readily absorbed when taken with food, so take each dose with meals or snacks to maximize its potential ability to burn fat. If trouble sleeping is keeping you stressed and reaching for midnight snacks, a dose at night may be best. Some brands, such as Cornbread Hemp, have both day and night formulations available.
Best Dosage of CBD for Weight Loss
The optimal dose of CBD to help you lose weight may vary from anywhere between 25mg to 200mg. Lower doses can protect you from unwanted body weight gain, while higher doses could help to restore your mitochondria and increase brown fat cells. If you haven’t taken CBD before, most brands recommend that you begin with a lower dose.
Best CBD for Weight Loss: The Verdict
Overall, Cornbread Hemp is our number one choice, as the use of hemp flowers only increases the concentration of beneficial cannabinoids and terpenes.
When searching for the best CBD oil for weight loss, a broad- or full-spectrum dose of cannabinoids is essential. This optimizes the range of benefits you can receive, such as increased conversion of white fat cells to brown fat, improved energy production, and less inflammation.
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Kire Stojkovski is a practicing medical doctor whose work has been published in some of the most respected medical journals.
Daniel Boyer is a practicing Doctor of medicine with a passion for medical research. He specializes in molecular biology, histology, and pharmacology.